Case report on clozapine-associated neuroleptic malignant syndrome
نویسندگان
چکیده
ABSTRACT This article summarizes the clinical manifestations of one case of clozapine-associated neuroleptic malignant syndrome and discusses its diagnosis, predisposing factors and treatment based on a literature review. Early identification and treatment is critical to lower the mortality of clozapine-associated neuroleptic malignant syndrome.
منابع مشابه
Clozapine and Neuroleptic Malignant Syndrome: Case Report and Risk Analysis of Monotherapy vs. Combination Therapy
Traditionally, patients who are considered treatment-resistant, or who present with more severe symptoms, are often considered for clozapine therapy. The combination of clozapine with another SGA, or on FGA, is also commonly utilized for such severe cases, and may be considered standard-of-care given the prevalence of these strategies. The following case report involves a chronically symptomati...
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The Neuroleptic Malignant Syndrome (NMS) is a medical emergency of infrequent presentation in the emergency department, which is associated with the use of psychiatric drugs, such as typical and atypical antipsychotics. Our case addresses a 55-year-old patient diagnosed with undifferentiated schizophrenia for 10 years, who had been receiving clozapine and clonazepam as part of their treatment. ...
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OBJECTIVE Neuroleptic malignant syndrome (NMS) is a rare life-threatening condition associated with the use of antipsychotics and other drugs that influence dopaminergic transmission. Although NMS is typically associated with classical antipsychotics, it can also be induced by atypical antipsychotics. In this paper, we report a case of NMS associated with clozapine use. CASE A 27-year-old mal...
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Objective: Neuroleptic malignant syndrome (NMS) is a rare, but life-threatening condition associated with the use of antipsychotics. Although NMS is mainly associated with typical antipsychotics, it can also be induced by atypical antipsychotics. In this paper, we report a case of NMS associated with clozapine use and describe the classic and atypical manifestations of NMS. The case and discuss...
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Clozapine, a commonly used atypical antipsychotic, can precipitate a severe withdrawal syndrome. In this report, we describe a case of delirium with catatonic features emerging after the immediate cessation of clozapine subsequent to concerns of developing neuroleptic malignant syndrome. After multiple treatments were found to be inefficacious, electroconvulsive therapy (ECT) was initiated, res...
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عنوان ژورنال:
دوره 24 شماره
صفحات -
تاریخ انتشار 2012